Worcestershire started their follow on innings on 123-3.Shanthakumaran Sreesanth took 3-56 including the wicket of Stephen Davies who had scored 62.
Ant Botha and Boyd Rankine chipped in with a wicket each before Chris Woakes took his total of wickets in the match to nine when he bowled Imran Arif for six.
This meant Worcestershire were all out for 271 and Warwickshire took the win.
Tomorrow, Warwicks take on Derbyshire in a Pro40 game at Edgbaston. The game is due to start at 12.45.