Some good bowling from Neil Carter and Heath Streak in their last County Championship game for Warwickshire had Lancashire all out for 311.
Laxman made 103 and Horton 71 whilst Neil Carter recorded figures of 5-62 in 17.4 overs with Heath 2-67 and Ant Botha 2-37.
Needing 205 to make Lancashire bat again, Warwicks were 125-2 at stumps with Ian Westwood making 50.
Warwicks have also announced that they are releasing Adam Sankey.